Mechanisms of Sucrose Metabolism in Streptococcus mutans.
نویسندگان
چکیده
منابع مشابه
Low sucrose levels promote extensive Streptococcus mutans-induced dental caries.
One-tenth percent sucrose significantly promotes dental caries induced by Streptococcus mutans in young gnotobiotic rats. Maximum caries activity was observed in rats provided a purified diet containing 3% sucrose.
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Streptococcus mutans, the major etiological agent in human dental caries, is capable of forming a biofilm, or dental plaque, on the tooth surface (Loesche, 1986; Tanzer et al., 2001). S. mutans generates large amounts of acid within dental plaque from fermentable dietary carbohydrates. During meals, the ingestion of carbohydrates causes the pH of the dental plaque to fall below 4.0. Acid accumu...
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Streptococcus mutans is known as a primary pathogen of dental caries, one of the most common human infectious diseases. Exopolysaccharide synthesis, adherence to tooth surface and biofilm formation are important physiological and virulence factors of S. mutans. In vitro comparative gene expression analysis was carried out to differentiate 10 selected genes known to be mostly involved in S. muta...
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Previous results have implicated an important role for the enzyme IIScr, the sucrose-specific permease, in the transport of sucrose by cariogenic Streptococcus mutans. The product of the scrB gene, sucrose-6-phosphate hydrolase (Suc-6PH), is required for the metabolism of phosphorylated sucrose. The results from the utilization of scrB::lacZ fusions in S. mutans GS-5 have suggested that sucrose...
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ژورنال
عنوان ژورنال: Japanese Journal of Oral Biology
سال: 1980
ISSN: 0385-0137
DOI: 10.2330/joralbiosci1965.22.16